SCIENTIFIC PROGRAMME

08:00 – 08:55
ROOM A | Case-based session
Organised by the ESC WG on Thrombosis Young Researchers
Chairs: Andrea Rubboli, Christina Christersson
Discussants: Eduardo Infante de Oliveira, Diana Gorog

• CC3 | Coronary Subclavian Steal Syndrome: an unusual cause of Acute Myocardial Infarction | Ana Isabel Pinho
• CC4 | Percutaneous Patent Foramen Ovale Closure after a Thrombotic Storm: A Case Report | David Sá-Couto
• CC17 | A catastrophic case of ischemic stroke and acute myocarditis in a young patient following mRNA COVID-19 vaccination: coincidence or consequence? | Jéni Quintal
• CC31 | Active gastrointestinal bleeding during STEMI: a management dilemma | Vanessa Lopes

ROOM B | Oral Presentations | Thrombosis and antithrombotic strategies I
Chairs: Ingebjorg Seljeflot, João Morais

• OP82 | Pre-treatment with Dual Antiplatelet Therapy in NSTE-ACS: not always, not ever | António Rocha de Almeida
• OP83 | Coronary Aspiration Thrombectomy: bringing back the old kid on the block | António Rocha de Almeida
• OP107 | Achieving higher efficacy without compromising safety with Factor XI inhibitors versus low-molecular-weight heparin for the prevention of venous thromboembolism in major orthopedic surgery | João Presume
• OP112 | Treatment of pulmonary embolism after paradoxical stroke | Mariana Martinho
• OP114 | Small-bore aspiration thrombectomy versus catheter-directed thrombolysis in intermediate-high risk acute Pulmonary Embolism | Mariana Martinho

ROOM C | Oral Presentations | Hematological biomarkers and prognostic implications
Chairs: Rory Koenen, Heleen Van Beusekom

• OP32 | The interplay between VWF, ADAMTS13 and TSP1, and their relation to clinical endpoints | Ellen Mathea Kirsch Warlo
• OP41 | High plasma von Willebrand factor concentration is associated with the development of bleeding complications in patients with polyvascular disease receiving multicomponent antithrombotic therapy | Elena Krivosheeva
• OP55 | Is White Blood Count a Good Marker to Coronary Disease Risk? | Débora Sá
• OP56 | Elevated White Blood Cells Count and C-Reactive Protein as markers for coronary heart disease prognosis | Débora Sá
• OP68 | Plasma fibrinogen independently predicts hypofibrinolysis in severe COVID-19 | Diana Schrick

09:00 – 10:30
ROOM A | Unrevealing the complexity of thrombosis in ACS
Chairs: Lina Badimon, Bruna Gigante

• Cardiac benefits of P2Y12 inhibitors beyond their antiplatelet properties | Gemma Vilahur
• Monocyte and macrophage subsets in coronary artery disease and beyond | Johann Wotja
• Epigenetics in atherothrombosis | Manuel Mayr
• Factor Xa and platelet activation | Daniel Caldeira

ROOM B | New concepts on old vascular disease
Chairs: Oliver Schlager, José Rodriguez Palomares

• Clinical Case | Giacomo Buso
• Fibromuscular Disease: no more reason to ignore it | Alexandre Persu
• Clinical Case | Giacomo Buso
• Aortic tortuosity: assessment and clinical consequences | Roland Van Kimmenade

10:30 – 11:00 | Posters & coffee break

11:00 – 12:25
ROOM A | Diabetes: targeting the increase in cardiovascular risk
Chairs: Carlo Patrono, Pedro Matos

• Myocardial Revascularization: A permanent challenge in Diabetes | Eduardo Infante de Oliveira 
• Managing glucose metabolism: does glycemia still matter? | Ramzi Ajjan
• How to stratify risk in diabetic patients | Pedro Matos
• Platelet inhibition | Bianca Rocca

ROOM B | Lower Extremity Artery Disease: improved management for better outcome
Chairs: Marco De Carlo, Frank Vermassen

• Optimal pharmacotherapy | Tristan Mirault
• Best Exercise training modalities | Lucia Mazzolai
• Endovascular revascularization? What we know and where we are heading to | Frank Vermassen
• Biomarkers in LEAD | Christian Heiss

12:30 – 13:45
ROOM A | Oral Presentations | Insights on vascular biology and disease
Chairs: Roland van Kimmenade, Tristan Mirault

• OP6 | Postoperative Myocardial Injury due to Platelet Reactivity in Patients undergoing Vascular Surgery | Kai Zheng
• OP48 | Sex-based differences in patients with peripheral arterial disease admitted for acute coronary syndrome – Insights from a multicentre national registry | Margarida Cabral
• OP75 | Impact of thoracic aortic calcification measured by computed tomography in clinical outcomes in patients undergoing cardiac surgery | Margarida Cabral
• OP89 | Vascular access computed tomography angiography-derived iliofemoral calcium volume in the evaluation of vascular and bleeding complications after transfemoral TAVI | Mariana Ribeiro Silva
• OP91 | Valve-in-valve TAVI for treatment of degenerated surgical aortic bioprosthesis | Mariana Ribeiro Silva
• OP121 | Aortic stiffness descriptors by cardiac magnetic resonance are correlated with mechanical testing of ex-vivo aortic aneurysms specimens | Aroa Ruiz Muñoz
• OP125 | Relation of non-invasively measured ankle-brachial index and pulse-wave velocity towards all-cause mortality in unselected emergency department patients – a prospective cross-sectional study | Oliver Schlager

ROOM B | Oral Presentations | Basic knowledge to understand thrombosis
Chairs: Gemma Vilahur, Johann Wotja

• OP3 | Growth differentiation factor-15 and bleeding complication risk in patients with coronary artery disease, receiving combined antithrombotic therapy | Elena Krivosheeva
• OP19 | Bi-directional cross talk between coagulation, fibrinolysis and inflammatory pathways in patients with ST-segment elevation myocardial infarction | Rahim Kanji
• OP46 | The effect of covid-19 vaccine on the endothelial function | Ahmed Makni
• OP90 | Pleiotropic effect of antiplatelet ticagrelor: expression of CYP4F2 in HUVEC and HepG2 | Ieva Ciapiene
• OP93 | Assessing different noncoding RNAs as markers of platelet reactivity | Clemens Gutmann
• OP105 | Endothelial dysfunction and alterations in erythrocyte function in a murine model of chronic heart failure | Tasnim Mohaissen
• OP64 | Elevated soluble glycoprotein VI, a specific predictor of bleeding risk in patients with chronic coronary syndromes undergoing percutaneous coronary intervention | Shqipdona Lahu

14:10 – 15:40
ROOM A | Antithrombotics in non-coronary interventions
Chairs: Christopher Twine, Tobias Geisler

• TAVI | Jurrien Ten Berg
• Left Atrial Appendage and PFO | Tobias Geisler
• Peripheral revascularization | Marco De Carlo
• Aortic endovascular therapy | Christopher Twine

ROOM B | Platelets in atherosclerosis and vascular biology: beyond thrombosis
Joint Session with the ESC WG on Atherosclerosis and Vascular Biology
Chairs: Marie-Luce Bochaton-Piallat, Gemma Vilahur

• Platelet-derived extracellular vesicles, chemokines and cell adhesion molecules in atherosclerosis | Rory Koenen
• Platelet-derived EVs as biological players after myocardial infarction – good or bad? | Christina Christersson
• The (not so) smooth muscle cell in atherosclerosis | Marie-Luce Bochaton-Piallat
• Vascular injury and repair and the journey of microthrombi following mechanical thrombectomy | Heleen Van Beusekom

15:40 – 16:00 | Posters & coffee break

16:00 – 17:25
ROOM A | Novel approaches in Lower Extremity Artery Disease (LEAD)
Joint Session with the European Society of Vascular Medicine
Chairs: Oliver Schlager, Victor Aboyans

• Supervised exercise training in LEAD: alternative or adjuvant to revascularization? | Christine Espinola-Klein
• Interventional management of calcified arterial lesions | Marianne Brodmann
• Regenerative therapy in no-option chronic limb threatening ischemia | Juraj Madaric
• Air pollution and Critical Limb Ischemia | Jill Belch

ROOM B | Strategies to prevent the continuum in CV Risk
Chairs: Francisco Araújo, Tobias Geisler

• Effects of exercise training on atherothrombotic risk | Ingebjorg Seljeflot
• The polypill in primary and secondary prevention. Where do we stand? | Diederick Grobbee
• Preventive strategies in patients with CKD | Rui Baptista
• Association between influenza vaccination and cardiovascular diseases | Tobias Geisler

17:30 – 17:55
ROOM A | Steen Husted Lecture
Chairs: Bianca Rocca, Lucia Mazzolai
• Current advances in ischemic stroke research and therapies | Heleen Van Beusekom

18:00 – 18:30
ROOM A | ESC WG on Thrombosis General Assembly
• General information to members of the Working Group (ongoing and upcoming activities)

08:00 – 08:55
ROOM A | Moderated posters
Chairs: Heleen Van Beusekom, Marco de Carlo

• PO12 | Premature myocardial infarction: a decade-long analysis of patients admitted to a single-center coronary care unit | Vanessa Lopes
• PO106 | Can we optimize d-dimer cut off value to predict pulmonary embolism in covid-19 patients? | Rafaela Fernandes
• PO52 | The Influence of the CYP2C9 polymorphisms on the treatment with clopidogrel: combined data from the POPular Genetics & POPular AGE trials | Wout van den Broek
• PO109 | Prognostic value of white blood cell count variation during in-hospital stay in STEMI patients: Insights from SCALIM Registry | Pierre Chenard
• PO122 | Predicting the rate of progressive dilation by wall shear stress in bicuspid aortic valve patients | José Rodriguez-Palomares

ROOM B | Oral Presentations | Thrombosis and antithrombotic strategies – II
Chair: Diana Gorog

• OP34 | A Case Series of patients with Pulmonary Embolism during post COVID-19 period | Elena Leonidou
• OP53 | Dose-related preprocedural patency of the infarct-related artery after zalunfiban (RUC-4) administration upon arrival at the catheterization laboratory in ST-elevation myocardial infarction: insights from the phase IIa study | Sem A.O.F. Rikken
• OP67 | Thrombotic Events in COVID-19 Patients Admitted at Chinese General Hospital and Medical Center | Joel Santos
• OP79 | Quality of life in patients after pulmonary embolism. Correlation with echocardiographic and biochemical parameters | Olga Kardakari
• OP126 | NOACs safety and efficacy in Adult Congenital Heart Disease | Cátia Oliveira

ROOM C | Oral Presentations | Brief tips useful for the clinicians
Chairs: Andrea Rubboli, Bruna Gigante

• OP69 | Chronotropic incompetence: still a suitable indicator? | Isabel Cruz
• OP81 | A STEMI case with sub-occlusive lesion and high thrombotic burden – discussing a tailored approach | Maria Rita Lima
• OP84 | Initial clinical experience with 6-hour enoxaparin regimen in opiate-treated patients undergoing primary percutaneous coronary intervention | Nadir Elamin
• OP96 | Impact of inflammatory and hematological factors to the left ventricule function, remodeling, and  clinical outcomes after the first myocardial infarction | Nina Korac
• OP10 | Pharmacological therapy in patients with myocardial infarction with nonobstructive coronary arteries (MINOCA): long-term prognosis | Vanessa Lopes

09:00 – 10:30
ROOM A | Update on antithrombotic strategies
Chairs: Sigrun Halvorsen, João Morais

• Antithrombotic strategies after AMI | Cristina Gavina
• Dual pathway in atherothrombotic disorders | João Morais
• Management of anti-thrombotic treatment in patients undergoing non-cardiac surgery | Sigrun Halvorsen
• Ongoing preclinical and clinical trials on FXIa and FXIIa | Hugo ten Cate

ROOM B | Aorta – What’s new since the 2014 guidelines? 
Chairs: Luís Mendes Pedro, Martin Czerny

• Genetics of Aortic Diseases | Julie Debacker
• New multimodality imaging techniques of the thoracic and abdominal aorta | José Rodriguez Palomares
• Type B aortic dissection: when to intervene | Martin Czerny
• Ruptured AAA: from prevention to intervention | Frank Vermassen

10:30 – 11:00 | Posters & coffee break

11:00 – 12:25
ROOM A | Optimizing outcomes in Vascular Surgery
Joint Session with the European Society of Vascular Surgery
Chairs: Lucia Mazzolai, João Morais

• Should we continue to screen cardiac diseases prior to peripheral revascularization? | Marco De Carlo
• Optimal medical treatment of candidates to Vascular Surgery in 2022 | Christopher Twine
• Peri-operative management of antithrombotic therapies | Christine Espinola-Klein
• Follow-up after vascular intervention | Christian Heiss

ROOM B | Predictive Biomarkers
Chairs: Bruna Gigante, Cristina Gavina

• Biomarkers of bleeding | Agneta Seigbahn
• Biomarkers of arterial thrombosis | Lina Badimon
• Biomarkers of fibrinolysis | Diana Gorog
• Biomarkers of venous thrombosis | Arina ten Cate-Hoek

12:30 – 13:00
ROOM A | Closing session

• Poster awards and closure of conference | João Morais, Andrea Rubboli, Oliver Schlager